Complications : Inflammatory Brain Disorder

Complications : Inflammatory Brain Disorder 150 150 Tony Guo


  • Increased ICP
    • Major cause of altered mental status
  • Residual neurologic dysfunction
    • Cranial nerves III, IV, VI, VII, or VIII can become dysfunctional
    • Sequelae varies by cranial nerve
  • Optic nerve (CN II) compressed by ↑ ICP
    • Papilledema with possible blindness
  • Ocular movements affected with irritation to nerves III, IV, and VI
    • Ptosis
    • Unequal pupils
    • Diplopia
  • CN V irritation
    • Sensory loss and loss of corneal reflex
  • Inflammation of CN VII
    • Facial paresis
  • Irritation of CN VIII
    • Tinnitus, vertigo, deafness
    • Hearing loss may be permanent
  • Hemiparesis, dysphagia, hemianopsia
  • Suspect the following if above do not resolve
    • Cerebral abscess, subdural empyema, subdural effusion, or persistent meningitis
  • Acute cerebral edema may cause
    • Seizures
    • CN III palsy
    • Bradycardia
    • Hypertensive coma
    • Death

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